Digital Fluorescence Imaging Using Cooled CCD Array Cameras invisible

The progress in solid state technologies has led to a range of CCD cameras from inexpensive video cameras to expensive scientific digital camera systems. The best choice (best value for money) depends heavily on the application. A state-ofthe-art camera’s performance is limited by the fundamental laws of nature. The various noise sources (photon statistics, thermal, readout and quantization) are examined to help you understand some specific operating conditions such as cooling and the choice of readout rates.